Endocrine Abstracts

Introduction: Treatment using radioactive iodine (RAI) is used in several thyroid diseases, including differentiated thyroid carcinoma (DTC). The most frequent adverse effects include acute gastrointestinal symptoms, sialadenitis, xerostomia, cervical pain, and cervical swelling. Chronic symptoms such as obstruction of the salivary ducts, pulmonary fibrosis or other primary malignant diseases are also described. A single case of change in tongue pigmentation / lingua villosa n...

Background: Serum thyroglobulin (Tg) is a reliable tumor marker in patients with differentiated thyroid carcinoma (DTC). Distant metastases of DTC, particularly in the lung, normally presents with higher levels of Tg, which is useful to follow the disease evolution. We describe a patient with DTC with lung metastases, with undetectable Tg and Tg-antibodies (TgAb).Clinical case: A 52-year-old woman underwent a subtotal thyroidectomy in 1993 because of a g...

Introduction: After treatment with Iodine-131(I-131) in differentiated thyroid cancer, a diagnostic scintigraphy is performed. We selected three cases in which bronchiectasis appear as a false-positive on the scintigraphy after treatment with I-131.Case reports: Three women, respectively 62, 64 and 65 years old, being followed in the Endocrinology Department of our Institute, with the diagnosis of papillary carcinoma of the thyroid, were submitted to I-1...

Introduction: The need to fast for the determination of lipid profile has been discussed in the past years, for several reasons – i) most of the day time is spent in a postprandial state; ii) the lipid concentrations seem to be only slightly affected by a normal meal; both fasting and postprandial can predict cardiovascular risk.Aim: Determine the influence of normal food intake on the lipid profile of diabetic patients.Method...

Introduction: Adrenal incidentalomas are asymptomatic adrenal masses found accidentally during routine examination, not intended for adrenal pathology evaluation. The functionality of these lesions must be further investigated. Rarely, bilateral adrenal nodular hyperplasia can be detected in a patient with Cushing’s disease. The authors present the case of a patient with possible autonomous cortisol secretion of adrenal origin that eventually emerged as Cushing’s dis...

Case report: 66 year old male with a neck growing mass performed an ultrasonography and fine-needle aspiration biopsy which was suspicious for papillary carcinoma. The patient was submitted to total thyroidectomy and central and left lateral compartments lymph node dissection. The histological report showed a follicular carcinoma of 9 cm, with multiple lymphovascular invasions and skeletal muscle invasion. There was a focally positive surgical margin and resected lymph nodes h...

Introduction: The definitive treatment of hyperthyroidism caused by toxic adenoma (TA) and toxic multinodular goiter (TMNG) is ablative therapy with radioactive iodine (RAI) or surgical resection of the hyperfunctioning thyroid nodules. Hypothyroidism after RAI therapy is a common complication.Objectives: To evaluate the prevalence and risk factors of hypothyroidism in patients undergoing RAI for AT and BMNT.Methods: A Multicentre ...